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The Type I Diabetes Genetics Consortium ‘Rapid Response’ family-based candidate gene study: strategy, genes selection, and main outcome

Candidate gene studies have long been the principal method for identification of susceptibility genes for type I diabetes (T1D), resulting in the discovery of HLA, INS, PTPN22, CTLA4, and IL2RA. However, many of the initial studies that relied on this strategy were largely underpowered, because of t...

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Detalhes bibliográficos
Main Authors: Julier, C, Akolkar, B, Concannon, P, Morahan, G, Nierras, C, Pugliese, A
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805447/
https://ncbi.nlm.nih.gov/pubmed/19956109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2009.99
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