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Retinoic-acid signalling in node ectoderm and posterior neural plate directs left–right patterning of somitic mesoderm

Somitogenesis requires bilateral rhythmic segmentation of paraxial mesoderm along the antero-posterior axis1. The location of somite segmentation depends on opposing signalling gradients of retinoic acid (generated by retinaldehyde dehydrogenase-2; Raldh2) anteriorly and fibroblast growth factor (FG...

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Main Authors: Sirbu, Ioan Ovidiu, Duester, Gregg
格式: Artigo
語言:Inglês
出版: 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805411/
https://ncbi.nlm.nih.gov/pubmed/16489341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1374
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