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Retinoic-acid signalling in node ectoderm and posterior neural plate directs left–right patterning of somitic mesoderm
Somitogenesis requires bilateral rhythmic segmentation of paraxial mesoderm along the antero-posterior axis1. The location of somite segmentation depends on opposing signalling gradients of retinoic acid (generated by retinaldehyde dehydrogenase-2; Raldh2) anteriorly and fibroblast growth factor (FG...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2006
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2805411/ https://ncbi.nlm.nih.gov/pubmed/16489341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1374 |
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