Recombinant human interferon-gamma reconstitutes defective phagocyte function in patients with chronic granulomatous disease of childhood.

Monocytes from 19 of 30 patients with the classic phenotype of chronic granulomatous disease of childhood (CGD) responded to 3 days of treatment in culture with recombinant human interferon-gamma (rHuIFN-gamma) at 100 units/ml by producing superoxide after stimulation with phorbol 12-myristate 13-ac...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Sechler, J M, Malech, H L, White, C J, Gallin, J I
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1988
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280539/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2838849/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.13.4874
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