The Aromatic Ring of Phenylalanine 334 Is Essential for Oligomerization of Vibrio vulnificus Hemolysin

Vibrio vulnificus hemolysin (VVH) is thought to be a member of the cholesterol-dependent cytolysin (CDC) family of pore-forming toxins. To date, the structure-function relationships of CDCs produced by Gram-negative bacteria remain largely unknown. We show here that the aromatic ring of phenylalanin...

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Detalhes bibliográficos
Main Authors: Kashimoto, Takashige, Ueno, Shunji, Koga, Takeshi, Fukudome, Shinji, Ehara, Hayato, Komai, Mayumi, Sugiyama, Hiroyuki, Susa, Nobuyuki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Structural Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805311/
https://ncbi.nlm.nih.gov/pubmed/19897654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01049-09
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