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Hyperglutamylation of Tubulin Can either Stabilize or Destabilize Microtubules in the Same Cell

In most eukaryotic cells, tubulin is subjected to posttranslational glutamylation, a conserved modification of unclear function. The glutamyl side chains form as branches of the primary sequence glutamic acids in two biochemically distinct steps: initiation and elongation. The length of the glutamyl...

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Detalhes bibliográficos
Main Authors: Wloga, Dorota, Dave, Drashti, Meagley, Jennifer, Rogowski, Krzysztof, Jerka-Dziadosz, Maria, Gaertig, Jacek
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805296/
https://ncbi.nlm.nih.gov/pubmed/19700636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00176-09
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