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Identification and sequencing of cDNA clones encoding the granule-associated serine proteases granzymes D, E, and F of cytolytic T lymphocytes.

Cytoplasmic granules of cytolytic T lymphocytes contain at least six related serine esterases (granzymes) that are released together with perforin, a pore-forming protein related to complement component C9, during target-cell lysis. Polyclonal antibodies were used to isolate a large number of cDNA c...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Jenne, D, Rey, C, Haefliger, J A, Qiao, B Y, Groscurth, P, Tschopp, J
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280526/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3260382/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.13.4814
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