CALCINEURIN INHIBITORS ACTIVATE THE PROTO-ONCOGENE RAS AND PROMOTE PRO-TUMORIGENIC SIGNALS IN RENAL CANCER CELLS

The development of cancer is a major problem in immunosuppressed patients, particularly after solid organ transplantation. We have recently shown that calcineurin inhibitors (CNI) used to treat transplant patients may play a critical role in the rapid progression of renal cancer. To examine the intr...

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Hlavní autoři: Datta, Dipak, Contreras, Alan G., Basu, Aninda, Dormond, Olivier, Flynn, Evelyn, Briscoe, David M., Pal, Soumitro
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805191/
https://ncbi.nlm.nih.gov/pubmed/19903851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-1404
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