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Titration of Variant HSV1-tk Gene Expression to Determine the Sensitivity of (18)F-FHBG PET Imaging in a Prostate Tumor
Because of its high selectivity and specificity for the imaging reporter probe 9-(4-(18)F-fluoro-3-[hydroxymethyl]butyl)guanine ((18)F-FHBG), the herpes simplex virus type 1 thymidine kinase (HSV1-tk) variant sr39tk is actively being studied as a PET reporter gene. We recently demonstrated the capab...
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主要な著者: | , , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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2009
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2805178/ https://ncbi.nlm.nih.gov/pubmed/19372484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.108.058438 |
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