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Macrophage phenotype and remodeling outcomes in response to biologic scaffolds with and without a cellular component

Recently, macrophages have been characterized as having an M1 or M2 phenotype based on receptor expression, cytokine and effector molecule production, and function. The effects of macrophage phenotype upon tissue remodeling following the implantation of a biomaterial are largely unknown. The objecti...

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Autores principales: Brown, Bryan N., Valentin, Jolene E., Stewart-Akers, Ann M., McCabe, George P., Badylak, Stephen F.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805023/
https://ncbi.nlm.nih.gov/pubmed/19121538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2008.11.040
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