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Targeting a Mimotope Vaccine to Activating Fcγ Receptors Empowers Dendritic Cells to Prime Specific CD8(+) T Cell Responses in Tumor-Bearing Mice

A major challenge for inducing antitumor immune responses with native or modified tumor/self-Ags in tumor-bearing hosts relates to achieving efficient uptake and processing by dendritic cells (DCs) to activate immune effector cells and limit the generation of regulatory T cell activity. We analyzed...

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Detalhes bibliográficos
Main Authors: Gil, Margaret, Bieniasz, Magdalena, Wierzbicki, Andrzej, Bambach, Barbara J., Rokita, Hanna, Kozbor, Danuta
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805007/
https://ncbi.nlm.nih.gov/pubmed/19846865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900364
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