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Cancer cells and normal cells differ in their requirements for Thoc1

The evolutionarily conserved TREX complex physically couples transcription, mRNP biogenesis, RNA processing, and RNA export for a subset of genes. HPR1 encodes an essential component of the S. cerevisiae TREX complex. HPR1 loss compromises transcriptional elongation, nuclear RNA export, and genome s...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Li, Yanping, Lin, Athena W., Zhang, Xiaojing, Wang, Yanqing, Wang, Xiaoling, Goodrich, David W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804983/
https://ncbi.nlm.nih.gov/pubmed/17638875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-06-3234
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