Gene Therapy with a Promoter Targeting Both Rods and Cones Rescues Retinal Degeneration Caused by AIPL1 Mutations

AIPL1 is required for the biosynthesis of photoreceptor phosphodiesterase (PDE)1–3. Gene defects in AIPL1 cause a heterogeneous set of conditions ranging from Leber Congenital Amaurosis (LCA), the severest form of early-onset retinal degeneration, to milder forms such as retinitis pigmentosa (RP) an...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Sun, Xun, Pawlyk, Basil, Xu, Xiaoyun, Liu, Xiaoqing, Bulgakov, Oleg, Adamian, Michael, Sandberg, Michael A., Khani, Shahrokh C., Tan, Mei-Hong, Smith, Alexander J., Ali, Robin R., Li, Tiansen
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804971/
https://ncbi.nlm.nih.gov/pubmed/19710705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2009.104
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados