Zebrafish Have a Competent p53-Dependent Nucleotide Excision Repair Pathway to Resolve Ultraviolet B–Induced DNA Damage in the Skin

Ultraviolet (UV) light is a primary environmental risk factor for melanoma, a deadly form of skin cancer derived from the pigmented cells called melanocytes. UVB irradiation causes DNA damage, mainly in the form of pyrimidine dimers (cis-syn cyclobutane pyrimidine dimers and pyrimidine (6-4) pyrimid...

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Bibliographic Details
Main Authors: Zeng, Zhiqiang, Richardson, Jennifer, Verduzco, Daniel, Mitchell, David L., Patton, E. Elizabeth
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2009
Subjects:
Cancer Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804931/
https://ncbi.nlm.nih.gov/pubmed/20047468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/zeb.2009.0611
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