Carcinoembryonic antigen is anchored to membranes by covalent attachment to a glycosylphosphatidylinositol moiety: identification of the ethanolamine linkage site.

The COOH-terminal amino acid of carcinoembryonic antigen (CEA) is shown to covalently link with ethanolamine, evidence consistent with the anchorage of CEA to the plasma membrane through a phosphatidylinositol-glycan tail. Purified CEA was digested with trypsin, and the resulting peptides were isola...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Hefta, S A, Hefta, L J, Lee, T D, Paxton, R J, Shively, J E
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1988
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280492/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3387431/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.13.4648
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