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Treatment of stroke with a synthetic liver X receptor agonist, TO901317, promotes synaptic plasticity and axonal regeneration in mice

In this study, we tested the hypothesis that TO901317 promotes synapse plasticity and axonal regeneration after stroke. Adult male C57BL/6J mice were subjected to middle cerebral artery occlusion (MCAo) and treated with or without TO901317 starting 24 h after MCAo daily for 14 days. Axonal damage an...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Chen, Jieli, Zacharek, Alex, Cui, Xu, Shehadah, Amjad, Jiang, Hao, Roberts, Cynthia, Lu, Mei, Chopp, Michael
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804900/
https://ncbi.nlm.nih.gov/pubmed/19724285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2009.187
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