Evidence for the involvement of the kainate receptor subunit GluR6 (GRIK2) in mediating behavioral displays related to behavioral symptoms of mania

The glutamate receptor 6 (GluR6 or GRIK2, one of the kainate receptors) gene resides in a genetic linkage region (6q21) associated with bipolar disorder (BPD), but its function in affective regulation is unknown. Compared with wild-type (WT) and GluR5 knockout (KO) mice, GluR6 KO mice were more acti...

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Detalhes bibliográficos
Main Authors: Shaltiel, G, Maeng, S, Malkesman, O, Pearson, B, Schloesser, RJ, Tragon, T, Rogawski, M, Gasior, M, Luckenbaugh, D, Chen, G, Manji, HK
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804880/
https://ncbi.nlm.nih.gov/pubmed/18332879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2008.20
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