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Cellular mechanisms underlying affective resiliency: The role of glucocorticoid receptor- and mitochondrially-mediated plasticity

Bipolar disorder (BPD) is a devastating psychiatric illness marked by recurrent episodes of mania and depression. While the underlying pathophysiology of BPD remains elusive, an abnormal hypothalamic–pituitary–adrenal (HPA) axis and dysfunctional glucocorticoid receptor (GR) signaling are considered...

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Autors principals: Hunsberger, Joshua G., Austin, Daniel R., Chen, Guang, Manji, Husseini K.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804877/
https://ncbi.nlm.nih.gov/pubmed/19595676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2009.06.103
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