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Chromium reduces the in vitro activity and fidelity of DNA replication mediated by the human cell DNA synthesome

Hexavalent chromium Cr(VI) is known to be a carcinogenic metal ion, with a complicated mechanism of action. It can be found within our environment in soil and water contaminated by manufacturing processes. Cr(VI) ion is readily taken up by cells, and is recognized to be both genotoxic and cytotoxic;...

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Detalhes bibliográficos
Main Authors: Dai, Heqiao, Liu, Jianying, Malkas, Linda H., Catalano, Jennifer, Alagharu, Srilakshmi, Hickey, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804861/
https://ncbi.nlm.nih.gov/pubmed/19371627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2008.12.028
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