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Fine Mapping of an Epilepsy Modifier Gene on Mouse Chromosome 19

Mutations in voltage-gated sodium channels are associated with several types of human epilepsy. Variable expressivity and penetrance are common features of inherited epilepsy caused by sodium channel mutations, suggesting that genetic modifiers may influence clinical severity. The mouse model Scn2a(...

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Main Authors: Bergren, Sarah K., Rutter, Elizabeth D., Kearney, Jennifer A.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804848/
https://ncbi.nlm.nih.gov/pubmed/19513789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-009-9193-6
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