CXCL5 is an adipose tissue derived factor that links obesity to insulin resistance

We show here high levels of expression and secretion of the chemokine CXCL5 in the macrophage fraction of white adipose tissue (WAT). Moreover, we find that CXCL5 is dramatically increased in serum of human obese compared to lean subjects. Conversely, CXCL5 concentration is decreased in obese subjec...

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Autores principales: Chavey, Carine, Lazennec, Gwendal, Lagarrigue, Sylviane, Clapé, Cyrielle, Iankova, Irena, Teyssier, Jacques, Annicotte, Jean-Sébastien, Schmidt, Julien, Mataki, Chikage, Yamamoto, Hiroyasu, Sanches, Rosario, Guma, Anna, Stich, Vladimir, Vitkova, Michaela, Jardin-Watelet, Bénédicte, Renard, Eric, Strieter, Robert, Tuthill, Antoinette, Hotamisligil, Gôkhan S., Vidal-Puig, Toni, Zorzano, Antonio, Langin, Dominique, Fajas, Lluis
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804846/
https://ncbi.nlm.nih.gov/pubmed/19356715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2009.03.002
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