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Reduction of Mouse Egg Surface Integrin Alpha(9) Subunit (ITGA9) Reduces the Egg's Ability to Support Sperm-Egg Binding and Fusion

The involvement of egg integrins in mammalian sperm-egg interactions has been controversial, with data from integrin inhibitor studies contrasting with evidence from knockouts showing that specific integrin subunits are not essential for fertility. An alpha(4)/alpha(9) (ITGA4/ITGA9) integrin subfami...

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Bibliographic Details
Main Authors: Vjugina, Ulyana, Zhu, Xiaoling, Oh, Eugene, Bracero, Nabal J., Evans, Janice P.
Format: Artigo
Language:Inglês
Published: Society for the Study of Reproduction, Inc. 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804834/
https://ncbi.nlm.nih.gov/pubmed/19129508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.108.075275
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