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Disruption of Mitochondrial Malate-Aspartate Shuttle Activity in Mouse Blastocysts Impairs Viability and Fetal Growth

The nutrient requirements and metabolic pathways used by the developing embryo transition from predominantly pyruvate during early cleavage stages to glucose at the blastocyst; however, the complexities involved in the regulation of metabolism at different developmental stages are not clear. The aim...

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Detalhes bibliográficos
Main Authors: Mitchell, Megan, Cashman, Kara S., Gardner, David K., Thompson, Jeremy G., Lane, Michelle
Formato: Artigo
Idioma:Inglês
Publicado em: Society for the Study of Reproduction, Inc. 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804819/
https://ncbi.nlm.nih.gov/pubmed/18971426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.108.069864
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