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Labeling strategies for (13)C-detected aligned-sample solid-state NMR of proteins

(13)C-detected solid-state NMR experiments have substantially higher sensitivity than the corresponding (15)N-detected experiments on stationary, aligned samples of isotopically labeled proteins. Several methods for tailoring the isotopic labeling are described that result in spatially isolated (13)...

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Detalles Bibliográficos
Main Authors: Fillip, Fabian V., Sinha, Neeraj, Jairam, Lena, Bradley, Joel, Opella, Stanley J.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804798/
https://ncbi.nlm.nih.gov/pubmed/19781966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmr.2009.08.012
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