In vitro suppression of the MMP-3 gene in normal and cytokine-treated human chondrosarcoma using small interfering RNA

BACKGROUND: Matrix metalloproteinase (MMPs) synthesized and secreted from connective tissue cells have been thought to participate in degradation of the extracellular matrix. Increased MMPs activities that degrade proteoglycans have been measured in osteoarthritis cartilage. This study aims to suppr...

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Main Authors: Nganvongpanit, Korakot, Chaochird, Patama, Siengdee, Puntita, Pothacharoen, Peraphan, Klunklin, Kasisin, Chomdej, Siriwadee, Mekchay, Supamit, Kongtaweelert, Prachya
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804682/
https://ncbi.nlm.nih.gov/pubmed/20034400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1749-799X-4-45
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