Regulation of interleukin 2 receptor alpha subunit (Tac or CD25 antigen) gene expression: binding of inducible nuclear proteins to discrete promoter sequences correlates with transcriptional activation.

Transfection of deleted forms of the human interleukin 2 receptor alpha subunit (IL-2R alpha; also called CD25 or Tac antigen) gene (IL2RA) promoter revealed a requirement for sequences 3' of base -317 for phytohemagglutinin- and phorbol 12-myristate 13-acetate (PMA)-induced promoter activation...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Lowenthal, J W, Böhnlein, E, Ballard, D W, Greene, W C
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1988
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280451/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3132714/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.12.4468
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