Autocrine Activation of Neuronal NMDA Receptors by Aspartate Mediates Dopamine- and cAMP-Induced CREB-Dependent Gene Transcription

cAMP can stimulate the transcription of many activity-dependent genes via activation of the transcription factor, cAMP response element-binding protein (CREB). However, in mouse cortical neuron cultures, prior to synaptogenesis, neither cAMP nor dopamine, which acts via cAMP, stimulated CREB-depende...

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Main Authors: Almeida, Luis E. F., Murray, Peter D., Zielke, H. Ronald, Roby, Clinton D., Kingsbury, Tami J., Krueger, Bruce K.
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2009
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804479/
https://ncbi.nlm.nih.gov/pubmed/19812345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1166-09.2009
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