Facilitation of Mitochondrial Outer and Inner Membrane Permeabilization and Cell Death in Oxidative Stress by a Novel Bcl-2 Homology 3 Domain Protein

We identified a sequence homologous to the Bcl-2 homology 3 (BH3) domain of Bcl-2 proteins in SOUL. Tissues expressed the protein to different extents. It was predominantly located in the cytoplasm, although a fraction of SOUL was associated with the mitochondria that increased upon oxidative stress...

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Bibliografiske detaljer
Main Authors: Szigeti, Andras, Hocsak, Eniko, Rapolti, Edit, Racz, Boglarka, Boronkai, Arpad, Pozsgai, Eva, Debreceni, Balazs, Bognar, Zita, Bellyei, Szabolcs, Sumegi, Balazs, Gallyas, Ferenc
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Mechanisms of Signal Transduction
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804370/
https://ncbi.nlm.nih.gov/pubmed/19901022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.015222
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