PB1 Domain Interaction of p62/Sequestosome 1 and MEKK3 Regulates NF-κB Activation

p62/Sequestosome 1 is a scaffold protein involved in the regulation of autophagy, trafficking of proteins to the proteasome, and activation of NF-κB. p62 encodes an N-terminal PB1 domain in addition to the ZZ domain, TRAF6-binding domain, LC3 interaction region, and ubiquitin-associated domain, each...

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Bibliographic Details
Main Authors: Nakamura, Kazuhiro, Kimple, Adam J., Siderovski, David P., Johnson, Gary L.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Mechanisms of Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804364/
https://ncbi.nlm.nih.gov/pubmed/19903815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.065102
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