Synthesis of Heparan Sulfate with Cyclophilin B-binding Properties Is Determined by Cell Type-specific Expression of Sulfotransferases

Cyclophilin B (CyPB) induces migration and adhesion of T lymphocytes via a mechanism that requires interaction with 3-O-sulfated heparan sulfate (HS). HS biosynthesis is a complex process with many sulfotransferases involved. N-Deacetylases/N-sulfotransferases are responsible for N-sulfation, which...

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Détails bibliographiques
Auteurs principaux: Deligny, Audrey, Denys, Agnès, Marcant, Adeline, Melchior, Aurélie, Mazurier, Joël, van Kuppevelt, Toin H., Allain, Fabrice
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2010
Sujets:
Glycobiology and Extracellular Matrices
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804328/
https://ncbi.nlm.nih.gov/pubmed/19940140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.018184
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