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Design of Synthetic Polymer Nanoparticles that Capture and Neutralize a Toxic Peptide

Designed polymer nanoparticles (NPs) capable of binding and neutralizing a biomacromolecular toxin are prepared. A library of copolymer NPs is synthesized from combinations of functional monomers. The binding capacity and affinity of the NPs are individually analyzed. NPs with optimized composition...

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Autors principals: Hoshino, Yu, Urakami, Takeo, Kodama, Takashi, Koide, Hiroyuki, Oku, Naoto, Okahata, Yoshio, Shea, Kenneth J.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804256/
https://ncbi.nlm.nih.gov/pubmed/19296557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/smll.200900186
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