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The Self-aggregation of A Polyalanine Octamer Promoted by Its C-Terminal Tyrosine And Probed By A Strongly Enhanced VCD Signal
[Image: see text] The 8-residue alanine oligopeptide, Ac-A(4)KA(2)Y-NH(2) (AKY8), was found to form amyloid-like fibrils upon incubation at room temperature in acidified aqueous solution, at peptide concentrations > 10 mM. The fibril solution exhibits an enhanced VCD couplet in the amide I’ band...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2804254/ https://ncbi.nlm.nih.gov/pubmed/19958029 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja908324m |
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