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No strict alignment is required between a transcriptional activator binding site and the "TATA box" of a yeast gene.

GAL4 is a transcriptional activator of the galactose metabolism genes in the yeast Saccharomyces cerevisiae. We show that GAL4 expressed in yeast activated transcription equally well when a single GAL4 binding site was placed at any of nine positions upstream of the GAL1 (galactokinase gene) "T...

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Detalhes bibliográficos
Main Authors: Ruden, D M, Ma, J, Ptashne, M
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC280407/
https://ncbi.nlm.nih.gov/pubmed/3132708
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