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Structure of chloramphenicol acetyltransferase at 1.75-A resolution.

Chloramphenicol acetyltransferase [acetyl-CoA:chloramphenicol O3-acetyltransferase; EC 2.3.1.28] is the enzyme responsible for high-level bacterial resistance to the antibiotic chloramphenicol. It catalyzes the transfer of an acetyl group from acetyl CoA to the primary hydroxyl of chloramphenicol. T...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Leslie, A G, Moody, P C, Shaw, W V
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1988
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280380/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3288984/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.12.4133
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