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Following dimethyl sulfoxide skin optical clearing dynamics with quantitative nonlinear multimodal microscopy

Second-harmonic generation (SHG) imaging is combined with coherent anti-Stokes Raman scattering (CARS) microscopy to follow the process of optical clearing in human skin ex vivo using dimethyl sulfoxide (DMSO) as the optical clearing agent. SHG imaging revealed that DMSO introduces morphological cha...

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Bibliographic Details
Main Authors: Zimmerley, Maxwell, McClure, R. Anthony, Choi, Bernard, Potma, Eric Olaf
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2803712/
https://ncbi.nlm.nih.gov/pubmed/19340127
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