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Review and Evaluation of Methods Correcting for Population Stratification with a Focus on Underlying Statistical Principles

When two or more populations have been separated by geographic or cultural boundaries for many generations, drift, spontaneous mutations, differential selection pressures and other factors may lead to allele frequency differences among populations. If these ‘parental’ populations subsequently come t...

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Detalhes bibliográficos
Main Authors: Tiwari, Hemant K., Barnholtz-Sloan, Jill, Wineinger, Nathan, Padilla, Miguel A., Vaughan, Laura K., Allison, David B.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2803696/
https://ncbi.nlm.nih.gov/pubmed/18382087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000119107
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