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Selective elimination of idiotype-binding cells in vivo by a drug-idiotype conjugate demonstrates the functional significance of these cells in immune regulation.

A receptor-specific cytotoxic drug delivery system has been used to eliminate idiotype-binding cells in vivo to ascertain the possible functional significance of these cells in regulating the humoral immune response to dextran. Protein M104E, a mouse myeloma protein that binds dextran, expresses a p...

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Main Authors: Abu-Hadid, M M, Bankert, R B, Mayers, G L
格式: Artigo
語言:Inglês
出版: 1988
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC280346/
https://ncbi.nlm.nih.gov/pubmed/2453882
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