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Physical association between the CD8 and HLA class I molecules on the surface of activated human T lymphocytes.

Immune recognition by cytotoxic effector T cells requires participation of the CD8 and major histocompatibility complex class I antigens. We found that the CD8 molecule is noncovalently associated with the HLA class I heavy chain on the surface of human T cells activated by Con A. Accordingly, anti-...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Bushkin, Y, Demaria, S, Le, J M, Schwab, R
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1988
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280345/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3131769/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.11.3985
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