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Cloning of the gene encoding the delta subunit of the human T-cell receptor reveals its physical organization within the alpha-subunit locus and its involvement in chromosome translocations in T-cell malignancy.

By taking advantage of "chromosomal walking" techniques, we have obtained clones that encompass the T-cell receptor (TCR) delta-chain gene. We analyzed clones spanning the entire J alpha region extending 115 kilobases 5' of the TCR alpha-chain constant region and have shown that the TCR delta-chain...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Isobe, M, Russo, G, Haluska, F G, Croce, C M
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1988
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280334/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2836865/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.11.3933
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