Decreased mitochondrial DNA content in blood samples of patients with stage I breast cancer

BACKGROUND: Alterations of mitochondrial DNA (mtDNA) have been implicated in carcinogenesis. We developed an accurate multiplex quantitative real-time PCR for synchronized determination of mtDNA and nuclear DNA (nDNA). We sought to investigate whether mtDNA content in the peripheral blood of breast...

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Hauptverfasser: Xia, Peng, An, Han-Xiang, Dang, Cheng-Xue, Radpour, Ramin, Kohler, Corina, Fokas, Emmanouil, Engenhart-Cabillic, Rita, Holzgreve, Wolfgang, Zhong, Xiao Yan
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2009
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2803198/
https://ncbi.nlm.nih.gov/pubmed/20025731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-454
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