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Tissue-Selective Regulation of Aromatase Expression by Calcitriol: Implications for Breast Cancer Therapy
Aromatase, the enzyme that catalyzes estrogen synthesis, is critical for the progression of estrogen receptor-positive breast cancer (BCa) in postmenopausal women. We show that calcitriol, the hormonally active form of vitamin D, regulates the expression of aromatase in a tissue-selective manner. Ca...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Endocrine Society
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2803154/ https://ncbi.nlm.nih.gov/pubmed/19906814 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2009-0855 |
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