Sulforaphane Increases Cyclin-Dependent Kinase Inhibitor, p21 Protein in Human Oral Carcinoma Cells and Nude Mouse Animal Model to Induce G(2)/M Cell Cycle Arrest

Previously, our group reported that sulforaphane (SFN), a naturally occurring chemopreventive agent from cruciferous vegetables, effectively inhibits the proliferation of KB and YD-10B human oral squamous carcinoma cells by causing apoptosis. In this study, treatment of 20 and 40 µM of SFN for 12 h...

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Autors principals: Kim, Jun-Hee, Han Kwon, Ki, Jung, Ji-Youn, Han, Hye-Suk, Hyun Shim, Jung, Oh, SeJun, Choi, Kyeong-Hee, Choi, Eun-Sun, Shin, Ji-Ae, Leem, Dae-Ho, Soh, Yunjo, Cho, Nam-Pyo, Cho, Sung-Dae
Format: Artigo
Idioma:Inglês
Publicat: the Society for Free Radical Research Japan 2010
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2803134/
https://ncbi.nlm.nih.gov/pubmed/20104266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3164/jcbn.09-65
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