A New Paradigm for Antimicrobial Host Defense Mediated by a Nitrated Cyclic Nucleotide

Nitric oxide (NO), produced by inducible NO synthase (iNOS) during infection, plays a crucial role in host defense mechanisms. Salmonella typhimurium infection in mice is associated with excessive production of NO from iNOS as a host defense response. An important cytoprotective and antimicrobial fu...

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Autores principales: Okamoto, Tatsuya, Khan, Shahzada, Oyama, Kohta, Fujii, Shigemoto, Sawa, Tomohiro, Akaike, Takaaki
Formato: Artigo
Lenguaje:Inglês
Publicado: the Society for Free Radical Research Japan 2010
Materias:
Serial Review
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2803128/
https://ncbi.nlm.nih.gov/pubmed/20104260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3164/jcbn.SR09-70
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