Nucleoside adducts are formed by cooperative reaction of acetaldehyde and alcohols: possible mechanism for the role of ethanol in carcinogenesis.

The exocyclic amino groups of ribonucleosides and deoxyribonucleosides react rapidly at ambient temperature with acetaldehyde and alcohols to yield mixed acetals [--NH--CH(CH3)OR]. Nucleotides and nucleoside di- and triphosphates also react. Depending on the nucleoside used and on the relative amoun...

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Bibliografische gegevens

Gepubliceerd in:	Proc Natl Acad Sci U S A
Hoofdauteurs:	Fraenkel-Conrat, H, Singer, B
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	National Academy of Sciences 1988
Onderwerpen:	Research Article
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280297/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3375239/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.11.3758
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