Structure of d-lactate dehydrogenase from Aquifex aeolicus complexed with NAD(+) and lactic acid (or pyruvate)

The crystal structure of d-lactate dehydrogenase from Aquifex aeolicus (aq_727) was determined to 2.12 Å resolution in space group P2(1)2(1)2(1), with unit-cell parameters a = 90.94, b = 94.43, c = 188.85 Å. The structure was solved by molecular replacement using the coenzyme-binding domain of Lacto...

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Autores principales: Antonyuk, Svetlana V., Strange, Richard W., Ellis, Mark J., Bessho, Yoshitaka, Kuramitsu, Seiki, Inoue, Yumiko, Yokoyama, Shigeyuki, Hasnain, S. Samar
Formato: Artigo
Lenguaje:Inglês
Publicado: International Union of Crystallography 2009
Materias:
RIKEN-UK structural genomics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802865/
https://ncbi.nlm.nih.gov/pubmed/20054113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309109044935
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