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Significance of Cellular Senescence in Aging and Cancer

Cellular senescence is a mechanism that induces an irreversible growth arrest in all somatic cells. Senescent cells are metabolically active but lack the capacity to replicate. Evolutionary theories suggest that cellular senescence is related to the organismal decline occurring in aging organisms. A...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Grimes, Angela, Chandra, Sathees B.C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Korean Cancer Association 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802848/
https://ncbi.nlm.nih.gov/pubmed/20057963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4143/crt.2009.41.4.187
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