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Down-regulation of transforming growth factor beta-2 expression is associated with the reduction of cyclosporin induced gingival overgrowth in rats treated with roxithromycin: an experimental study

BACKGROUND: Gingival overgrowth (GO) is a common side effect of the chronic use of cyclosporine (CsA), an immunosuppressant widely used to prevent rejection in transplant patients. Recent studies have reported elevated levels of specific cytokines in gingival overgrowth tissue, particularly TGF-beta...

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Detalhes bibliográficos
Main Authors: Condé, Simone Aparecida Probst, Bastos, Marcus Gomes, Vieira, Beatriz Julião, Aarestrup, Fernando Monteiro
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802586/
https://ncbi.nlm.nih.gov/pubmed/19995419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6831-9-33
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