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Vaccination with Vif-deleted Feline Immunodeficiency Virus Provirus, GM-CSF, and TNF-α Plasmids Preserves Global CD4 T Lymphocyte Function after Challenge with FIV

Feline immunodeficiency virus (FIV) DNA vaccine approaches that included a vif-deleted FIV provirus (FIV-pPPRΔvif) and feline cytokine expression plasmids were tested for immunogenicity and efficacy by immunization of specific pathogen free cats. Vaccine protocols included FIV-pPPRΔvif plasmid alone...

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Bibliographic Details
Main Authors: Maksaereekul, Saipiroon, Dubie, Robert A., Shen, Xiaoying, Kieu, Hung, Dean, Gregg A., Sparger, Ellen E.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802579/
https://ncbi.nlm.nih.gov/pubmed/19464559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2009.03.081
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