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Rearrangement and expression of endogenous immunoglobulin genes occur in many murine B cells expressing transgenic membrane IgM.

Transgenic mice carrying immunoglobulin genes coding for mu heavy chain and kappa light chain have been used to study the mechanisms involved in allelic and isotypic exclusion. We report here that individual cells from transgenic mice carrying a functionally rearranged mu heavy chain gene (capable o...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Stall, A M, Kroese, F G, Gadus, F T, Sieckmann, D G, Herzenberg, L A
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1988
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280250/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3130629/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.10.3546
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