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Mechanisms of Inhibition of T-Type Calcium Current in the Reticular Thalamic Neurons by 1-Octanol: Implication of the Protein Kinase C Pathway

Recent studies indicate that T-type calcium channels (T-channels) in the thalamus are cellular targets for general anesthetics. Here, we recorded T-currents and underlying low-threshold calcium spikes from neurons of nucleus reticularis thalami (nRT) in brain slices from young rats and investigated...

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Detalhes bibliográficos
Main Authors: Joksovic, Pavle M., Choe, Won Joo, Nelson, Michael T., Orestes, Peihan, Brimelow, Barbara C., Todorovic, Slobodan M.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802428/
https://ncbi.nlm.nih.gov/pubmed/19846748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.109.059931
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