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Knockdown of RCAN1.4 Increases Susceptibility to FAS-mediated and DNA-damage-induced Apoptosis by Upregulation of p53 Expression

Despite the potential importance of the human regulator of calcineurin 1 (RCAN-1) gene in the modulation of cell survival under stress, little is known about its role in death-inducing signal pathways. In this study, we addressed the effects of RCAN1.4 knockdown on cellular susceptibility to apoptos...

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Bibliographic Details
Main Authors: Kim, Young Sun, Lee, Hong Joon, Jang, Chorong, Kim, Ho-Shik, Cho, Young-Jin
Format: Artigo
Language:Inglês
Published: The Korean Physiological Society and The Korean Society of Pharmacology 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802310/
https://ncbi.nlm.nih.gov/pubmed/20054496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2009.13.6.483
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